The average train between Mendrisio and Heidelberg takes 6h 38m and the fastest train takes 6h 4m. The train service runs several times per day from Mendrisio to Heidelberg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Mendrisio and Heidelberg. The earliest departure is at 5:34 AM in the morning, and the last departure from Mendrisio is at 9:41 PM which arrives into Heidelberg at 7:23 AM. All services require a transfer at Lugano and take an average of 6h 38m. The schedules shown below are for the next available departures.



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6h 4m • 3 changesWant to know about travelling from Mendrisio to Heidelberg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mendrisio to Heidelberg. However, there are services departing from Lugano station and arriving at Mannheim, Hauptbahnhof station via Basel SBB station. The journey, including transfers, takes approximately 6h 38m.
Mendrisio to Heidelberg train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Lugano station.
Mendrisio to Heidelberg train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Mannheim, Hauptbahnhof station.
Book your Mendrisio to Heidelberg train tickets online with Omio.
The distance between Mendrisio and Heidelberg is 393.9 km. The road distance is 521 km.
You can take a train from Mendrisio to Heidelberg, Hauptbahnhof via Lugano, Basel SBB, and Mannheim, Hauptbahnhof in around 7h 7m.