Mendrisio to Iseo Trains

Trip Overview

The average train between Mendrisio and Iseo takes 3h 45m and the fastest train takes 2h 42m. The train service runs several times per day from Mendrisio to Iseo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 45m
Duration: 166 km
Distance: €37
Average price: Every 3 hours
Frequency

Train

best

Take the train from Mendrisio to Milano Centraletrain
Take the train from Milano Centrale to Bresciatrain
Take the train from Brescia to Iseotrain S31 / ...

3h 17m

€31–50

Mendrisio to Iseo train times

Trains run every 3 hours between Mendrisio and Iseo. The earliest departure is at 6:18 AM in the morning, and the last departure from Mendrisio is at 8:18 PM which arrives into Iseo at 6:27 AM. All services require a transfer at Milano Centrale and take an average of 3h 45m. The schedules shown below are for the next available departures.

Departing Thursday, November 5, 2026

6:18 AM → 9:27 AM
3h 9m • 2 changes
8:18 AM → 11:27 AM
3h 9m • 2 changes
10:18 AM → 1:27 PM
3h 9m • 2 changes
11:18 AM → 2:01 PM
2h 43m • 2 changes
Show more

Departing Friday, November 6, 2026

6:18 AM → 9:27 AM
3h 9m • 2 changes
8:18 AM → 11:27 AM
3h 9m • 2 changes
10:18 AM → 1:27 PM
3h 9m • 2 changes
11:18 AM → 2:01 PM
2h 43m • 2 changes
Show more

Departing Saturday, November 7, 2026

6:18 AM → 9:27 AM
3h 9m • 2 changes
8:18 AM → 11:27 AM
3h 9m • 2 changes
10:18 AM → 1:27 PM
3h 9m • 2 changes
11:18 AM → 2:01 PM
2h 43m • 2 changes
Show more

Departing Sunday, November 8, 2026

6:18 AM → 9:27 AM
3h 9m • 2 changes
8:18 AM → 11:27 AM
3h 9m • 2 changes
10:18 AM → 1:27 PM
3h 9m • 2 changes
11:18 AM → 2:25 PM
3h 7m • 2 changes
Show more

Departing Monday, November 9, 2026

6:18 AM → 9:27 AM
3h 9m • 2 changes
8:18 AM → 11:27 AM
3h 9m • 2 changes
10:18 AM → 1:27 PM
3h 9m • 2 changes
11:18 AM → 2:01 PM
2h 43m • 2 changes
Show more

Departing Tuesday, November 10, 2026

6:18 AM → 9:27 AM
3h 9m • 2 changes
8:18 AM → 11:27 AM
3h 9m • 2 changes
10:18 AM → 1:27 PM
3h 9m • 2 changes
11:18 AM → 2:01 PM
2h 43m • 2 changes
Show more

Departing Wednesday, November 11, 2026

6:18 AM → 9:27 AM
3h 9m • 2 changes
8:18 AM → 11:27 AM
3h 9m • 2 changes
10:18 AM → 1:27 PM
3h 9m • 2 changes
11:18 AM → 2:01 PM
2h 43m • 2 changes
Show more

Frequently asked questions

Want to know about travelling from Mendrisio to Iseo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.