Mendrisio to Rome Trains

Mendrisio to Rome trains

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Trip Overview

The average train between Mendrisio and Rome takes 5h 32m and the fastest train takes 4h 42m. There is a train service every few hours from Mendrisio to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 32m
Duration: 639 km
Distance: €103
Average price: Hourly
Frequency

Train

best

Take the train from Mendrisio to Milano Centraletrain Re80
Take the train from Milano Centrale to Roma Terminitrain 9995 / ...

4h 19m

€85–150

Mendrisio to Rome train times

Trains run hourly between Mendrisio and Rome. The earliest departure is at 6:18 AM in the morning, and the last departure from Mendrisio is at 9:18 PM which arrives into Rome at 9:19 AM. All services require a transfer, and take on average 5h 32m. The schedules shown below are for the next available departures.

Departing Sunday, November 1, 2026

9:18 PM → 9:19 AM
Arrives next day
12h 1m • 1 change

Departing Monday, November 2, 2026

6:18 AM → 11:00 AM
4h 42m • 1 change
7:18 AM → 12:19 PM
5h 1m • 1 change
8:18 AM → 1:24 PM
5h 6m • 1 change
9:18 AM → 2:30 PM
5h 12m • 1 change
Show more

Departing Tuesday, November 3, 2026

6:18 AM → 11:00 AM
4h 42m • 1 change
7:18 AM → 12:19 PM
5h 1m • 1 change
8:18 AM → 1:24 PM
5h 6m • 1 change
9:18 AM → 2:30 PM
5h 12m • 1 change
Show more

Departing Wednesday, November 4, 2026

6:18 AM → 11:00 AM
4h 42m • 1 change
7:18 AM → 12:19 PM
5h 1m • 1 change
8:18 AM → 1:24 PM
5h 6m • 1 change
9:18 AM → 2:30 PM
5h 12m • 1 change
Show more

Departing Thursday, November 5, 2026

6:18 AM → 11:00 AM
4h 42m • 1 change
7:18 AM → 12:19 PM
5h 1m • 1 change
8:18 AM → 1:24 PM
5h 6m • 1 change
9:18 AM → 2:30 PM
5h 12m • 1 change
Show more

Departing Friday, November 6, 2026

6:18 AM → 11:00 AM
4h 42m • 1 change
7:18 AM → 12:19 PM
5h 1m • 1 change
8:18 AM → 1:24 PM
5h 6m • 1 change
9:18 AM → 2:30 PM
5h 12m • 1 change
Show more

Departing Saturday, November 7, 2026

6:18 AM → 11:00 AM
4h 42m • 1 change
7:18 AM → 12:19 PM
5h 1m • 1 change
8:18 AM → 1:24 PM
5h 6m • 1 change
9:18 AM → 2:30 PM
5h 12m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Mendrisio to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.