Mendrisio to Rome Trains

Mendrisio to Rome trains

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Trip Overview

The average train between Mendrisio and Rome takes 6h 24m and the fastest train takes 5h 1m. There is a train service every few hours from Mendrisio to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

6h 24m
Duration: 619 km
Distance: €125
Average price: Hourly
Frequency

Train

best

Take the train from Mendrisio to Milano Centraletrain Re80
Take the train from Milano Centrale to Roma Terminitrain Fr / ...

4h 15m

€91–234

Mendrisio to Rome train times

Trains run hourly between Mendrisio and Rome. The earliest departure is at 6:18 AM in the morning, and the last departure from Mendrisio is at 9:18 PM which arrives into Rome at 9:25 AM. All services require a transfer, and take on average 6h 24m. The schedules shown below are for the next available departures.

Departing Monday, August 10, 2026

6:18 AM → 12:10 PM
5h 52m • 1 change
7:18 AM → 1:15 PM
5h 57m • 1 change
8:18 AM → 2:20 PM
6h 2m • 1 change
9:18 AM → 3:15 PM
5h 57m • 1 change
Show more

Departing Tuesday, August 11, 2026

6:18 AM → 12:10 PM
5h 52m • 1 change
7:18 AM → 1:15 PM
5h 57m • 1 change
8:18 AM → 2:20 PM
6h 2m • 1 change
9:18 AM → 3:15 PM
5h 57m • 1 change
Show more

Departing Wednesday, August 12, 2026

6:18 AM → 12:10 PM
5h 52m • 1 change
7:18 AM → 1:15 PM
5h 57m • 1 change
8:18 AM → 2:20 PM
6h 2m • 1 change
9:18 AM → 3:15 PM
5h 57m • 1 change
Show more

Departing Thursday, August 13, 2026

6:18 AM → 12:10 PM
5h 52m • 1 change
7:18 AM → 1:15 PM
5h 57m • 1 change
8:18 AM → 2:20 PM
6h 2m • 1 change
9:18 AM → 3:15 PM
5h 57m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Mendrisio to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.