Mendrisio to Spoleto Trains

Mendrisio to Spoleto trains

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Trip Overview

The average train between Mendrisio and Spoleto takes 8h 27m and the fastest train takes 6h 28m. The train service runs several times per day from Mendrisio to Spoleto. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

8h 27m
Duration: 735 km
Distance: €120
Average price: Every 4 hours
Frequency

Train via Rome

best

Take the train from Mendrisio to Milano Centraletrain
Take the train from Milano Centrale to Roma Tiburtinatrain
Take the train from Roma Tiburtina to Spoletotrain

6h 41m

€97–164

Mendrisio to Spoleto train times

Trains run every 4 hours between Mendrisio and Spoleto. The earliest departure is at 6:18 AM in the morning, and the last departure from Mendrisio is at 9:18 PM which arrives into Spoleto at 11:02 AM. All services require a transfer at Milano Centrale and take an average of 8h 27m. The schedules shown below are for the next available departures.

Departing Monday, November 2, 2026

9:18 PM → 11:02 AM
Arrives next day
13h 44m • 2 changes

Departing Tuesday, November 3, 2026

6:18 AM → 1:51 PM
7h 33m • 2 changes
8:18 AM → 2:55 PM
6h 37m • 2 changes
10:18 AM → 4:46 PM
6h 28m • 2 changes
11:18 AM → 6:31 PM
7h 13m • 2 changes
Show more

Departing Wednesday, November 4, 2026

6:18 AM → 1:51 PM
7h 33m • 2 changes
8:18 AM → 2:55 PM
6h 37m • 2 changes
10:18 AM → 4:46 PM
6h 28m • 2 changes
11:18 AM → 6:31 PM
7h 13m • 2 changes
Show more

Departing Thursday, November 5, 2026

6:18 AM → 1:51 PM
7h 33m • 2 changes
8:18 AM → 2:55 PM
6h 37m • 2 changes
10:18 AM → 4:46 PM
6h 28m • 2 changes
11:18 AM → 6:31 PM
7h 13m • 2 changes
Show more

Departing Friday, November 6, 2026

6:18 AM → 1:51 PM
7h 33m • 2 changes
8:18 AM → 2:55 PM
6h 37m • 2 changes
10:18 AM → 4:46 PM
6h 28m • 2 changes
11:18 AM → 6:31 PM
7h 13m • 2 changes
Show more

Departing Saturday, November 7, 2026

6:18 AM → 1:51 PM
7h 33m • 2 changes
8:18 AM → 2:55 PM
6h 37m • 2 changes
10:18 AM → 4:46 PM
6h 28m • 2 changes
11:18 AM → 6:31 PM
7h 13m • 2 changes
Show more

Departing Sunday, November 8, 2026

6:18 AM → 1:03 PM
6h 45m • 2 changes
8:18 AM → 2:55 PM
6h 37m • 2 changes
10:18 AM → 4:46 PM
6h 28m • 2 changes
11:18 AM → 6:32 PM
7h 14m • 2 changes
Show more

Departing Monday, November 9, 2026

6:18 AM → 1:51 PM
7h 33m • 2 changes
8:18 AM → 2:55 PM
6h 37m • 2 changes
10:18 AM → 4:46 PM
6h 28m • 2 changes
11:18 AM → 6:31 PM
7h 13m • 2 changes
Show more

Frequently asked questions

Want to know about travelling from Mendrisio to Spoleto? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.