The average train between Mesagne and Monopoli takes 1h 30m and the fastest train takes 1h 3m. The train service runs several times per day from Mesagne to Monopoli. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Mesagne and Monopoli. The earliest departure is at 6:18 AM in the morning, and the last departure from Mesagne is at 7:44 PM which arrives into Monopoli at 9:29 PM. All services require a transfer, and take on average 1h 30m. The schedules shown below are for the next available departures.

1h 51m • 1 change
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1h 27m • 1 changeWant to know about travelling from Mesagne to Monopoli? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mesagne to Monopoli. However, there are services departing from Mesagne station and arriving at Monopoli station via Brindisi. The journey, including transfers, takes approximately 1h 30m.
Mesagne to Monopoli train services, operated by Trenitalia, depart from Mesagne station.
Mesagne to Monopoli train services, operated by Trenitalia, arrive at Monopoli station.
Book your Mesagne to Monopoli train tickets online with Trenitalia and Trenitalia Intercity.
The distance between Mesagne and Monopoli is 61.1 km. The road distance is 85 km.
You can take a train from Mesagne to Monopoli via Brindisi in around 1h 13m.