The average train between Mestre and Pescara takes 4h 41m and the fastest train takes 4h 27m. There is a train service every few hours from Mestre to Pescara. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Mestre and Pescara. The earliest departure is at 7:17 AM in the morning, and the last departure from Mestre is at 6:17 PM which arrives into Pescara at 11:10 PM. All services require a transfer, and take on average 4h 41m. The schedules shown below are for the next available departures.

4h 27m • 1 change

4h 27m • 1 change

5h 25m • 1 change

4h 27m • 1 change

4h 27m • 1 change

4h 27m • 1 change

5h 25m • 1 change

4h 27m • 1 change

4h 27m • 1 change

4h 27m • 1 change

5h 25m • 1 change

4h 27m • 1 change

4h 27m • 1 change

4h 27m • 1 change

5h 25m • 1 change

4h 27m • 1 change
Want to know about travelling from Mestre to Pescara? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Mestre to Pescara. However, there are services departing from Mestre station and arriving at Pescara station via Bologna Centrale. The journey, including transfers, takes approximately 4h 41m.
Mestre to Pescara train services, operated by ItaloTreno, depart from Venezia Mestre station.
Mestre to Pescara train services, operated by ItaloTreno, arrive at Pescara Centrale station.
Book your Mestre to Pescara train tickets online with ItaloTreno, Trenitalia Frecce and Trenitalia Intercity.
The distance between Mestre and Pescara is 371.9 km. The road distance is 501 km.
You can take a train from Venezia Mestre to Pescara Centrale via Bologna Centrale in around 4h 39m.