The average train between Meziměstí and Prague takes 4h 16m and the fastest train takes 3h 24m. The train service runs several times per day from Meziměstí to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Meziměstí and Prague. The earliest departure is at 6:18 AM in the morning, and the last departure from Meziměstí is at 8:18 PM which arrives into Prague at 7:42 AM. All services require a transfer, and take on average 4h 16m. The schedules shown below are for the next available departures.

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Want to know about travelling from Meziměstí to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Meziměstí to Prague. However, there are services departing from Meziměstí station and arriving at Prague station via Starkoc. The journey, including transfers, takes approximately 4h 16m.
Meziměstí to Prague train services, operated by České dráhy (ČD), depart from Mezimesti station.
Meziměstí to Prague train services, operated by České dráhy (ČD), arrive at Praha Hlavni Nadrazi station.
The distance between Meziměstí and Prague is 142.2 km. The road distance is 188 km.
You can take a train from Mezimesti to Praha Hlavni Nadrazi via Starkoc in around 3h 59m.