The average train between Milan and Ascoli Piceno takes 8h 29m and the fastest train takes 5h 58m. The train service runs several times per day from Milan to Ascoli Piceno. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Milan and Ascoli Piceno. The earliest departure is at 11:40 AM in the morning, and the last departure from Milan is at 5:00 PM which arrives into Ascoli Piceno at 7:56 AM. All services require a transfer at Reggio Emilia Av and take an average of 8h 29m. The schedules shown below are for the next available departures.


6h 8m • 2 changes


6h 38m • 2 changes
Arrives next day


15h 21m • 2 changes


5h 58m • 2 changes


6h 18m • 2 changes
Arrives next day


14h 56m • 2 changes
Want to know about travelling from Milan to Ascoli Piceno? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Milan to Ascoli Piceno. However, there are services departing from Milan station and arriving at Ascoli Piceno station via Reggio Emilia Av. The journey, including transfers, takes approximately 8h 29m.
Milan to Ascoli Piceno train services, operated by Trenitalia Frecce, depart from Milano Centrale station.
Milan to Ascoli Piceno train services, operated by Trenitalia Frecce, arrive at Ascoli Piceno station.
Book your Milan to Ascoli Piceno train tickets online with Trenitalia Frecce and Trenitalia.
The distance between Milan and Ascoli Piceno is 454.4 km. The road distance is 534 km.
You can take a train from Milano Centrale to Ascoli Piceno via Reggio Emilia Av and Ancona in around 6h 26m.