The average train between Milan and Avezzano takes 5h 47m and the fastest train takes 5h 2m. The train service runs several times per day from Milan to Avezzano. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 4 times a day between Milan and Avezzano. The earliest departure is at 5:20 AM in the morning, and the last departure from Milan is at 8:35 PM which arrives into Avezzano at 11:06 AM. All services require a transfer, and take on average 5h 47m. The schedules shown below are for the next available departures.

5h 46m • 1 change
5h 42m • 1 change
5h 2m • 1 change
5h 18m • 1 changeWant to know about travelling from Milan to Avezzano? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Milan to Avezzano. However, there are services departing from Milan station and arriving at Avezzano station via Roma Termini. The journey, including transfers, takes approximately 5h 47m.
Milan to Avezzano train services, operated by Trenitalia Frecce, depart from Milano Centrale station.
Milan to Avezzano train services, operated by Trenitalia Frecce, arrive at Avezzano station.
Book your Milan to Avezzano train tickets online with Trenitalia Frecce and Trenitalia.
The distance between Milan and Avezzano is 511.5 km. The road distance is 667 km.
You can take a train from Milano Centrale to Avezzano via Roma Termini in around 6h 7m.