The average train between Milan and Avezzano takes 7h 27m and the fastest train takes 5h 35m. The train service runs several times per day from Milan to Avezzano. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Milan and Avezzano. The earliest departure is at 7:45 AM in the morning, and the last departure from Milan is at 7:40 PM which arrives into Avezzano at 9:15 AM. All services require a transfer, and take on average 7h 27m. The schedules shown below are for the next available departures.

6h 5m • 1 change

6h 6m • 1 change

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5h 55m • 1 change

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6h 5m • 1 change

6h 6m • 1 change

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5h 55m • 1 change

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5h 45m • 1 change

6h • 1 change

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5h 55m • 1 change
Want to know about travelling from Milan to Avezzano? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Milan to Avezzano. However, there are services departing from Milan station and arriving at Avezzano station via Roma Tiburtina. The journey, including transfers, takes approximately 7h 27m.
Milan to Avezzano train services, operated by ItaloTreno, depart from Milano Centrale station.
Milan to Avezzano train services, operated by ItaloTreno, arrive at Avezzano station.
Book your Milan to Avezzano train tickets online with ItaloTreno and Trenitalia.
The distance between Milan and Avezzano is 511.5 km. The road distance is 662 km.
You can take a train from Milano Centrale to Avezzano via Roma Tiburtina in around 5h 19m.