The average train between Milan and Colosseum takes 4h 44m and the fastest train takes 3h 16m. There is a train service every few hours from Milan to Colosseum. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Milan and Colosseum. The earliest departure is at 4:40 AM at night, and the last departure from Milan is at 8:35 PM which arrives into Colosseum at 5:49 AM. All services require a transfer at Rome Termini and take an average of 4h 44m. The schedules shown below are for the next available departures.

4h 54m • 1 change

4h 41m • 1 change

4h 42m • 1 change

4h 36m • 1 change

4h 54m • 1 change

4h 41m • 1 change

4h 42m • 1 change

4h 36m • 1 change

4h 54m • 1 change

4h 41m • 1 change

4h 42m • 1 change

4h 36m • 1 change
Want to know about travelling from Milan to Colosseum? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Milan to Colosseum. However, there are services departing from Milan station and arriving at Colosseum station via Roma Termini. The journey, including transfers, takes approximately 4h 44m.
Milan to Colosseum train services, operated by Trenitalia Frecce, depart from Milano Centrale station.
Milan to Colosseum train services, operated by Trenitalia Frecce, arrive at Roma Termini station.
The distance between Milan and Colosseum is 477.9 km. The road distance is 563 km.
Trenitalia Frecce operates a train from Milano Centrale to Roma Termini every 30 minutes. Tickets cost €80–170 and the journey takes 3h 4m. ItaloTreno also services this route once daily.