The average train between Milan and Guidonia takes 4h 53m and the fastest train takes 3h 55m. The train service runs several times per day from Milan to Guidonia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Milan and Guidonia. The earliest departure is at 5:40 AM in the morning, and the last departure from Milan is at 7:40 PM which arrives into Guidonia at 6:04 AM. All services require a transfer, and take on average 4h 53m. The schedules shown below are for the next available departures.

4h 23m • 1 change
3h 55m • 1 changeArrives next day

10h 1m • 1 change
4h 22m • 1 change
4h 25m • 1 change
3h 59m • 1 change
4h 21m • 1 change
4h 22m • 1 change
4h 25m • 1 change
3h 59m • 1 change
4h 21m • 1 change
4h 22m • 1 change
4h 25m • 1 change
3h 59m • 1 change
4h 21m • 1 change
3h 59m • 1 change
4h 4m • 1 change
5h 2m • 1 change
3h 55m • 1 change
4h 22m • 1 change
4h 25m • 1 change
3h 59m • 1 change
4h 21m • 1 changeWant to know about travelling from Milan to Guidonia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Milan to Guidonia. However, there are services departing from Milan station and arriving at Guidonia station via Roma Tiburtina. The journey, including transfers, takes approximately 4h 53m.
Milan to Guidonia train services, operated by ItaloTreno, depart from Milano Centrale station.
Milan to Guidonia train services, operated by ItaloTreno, arrive at Roma Tiburtina station.
Book your Milan to Guidonia train tickets online with ItaloTreno and Trenitalia.
The distance between Milan and Guidonia is 478.9 km. The road distance is 579 km.
ItaloTreno operates a train from Milano Centrale to Roma Tiburtina hourly. Tickets cost €70–140 and the journey takes 3h 4m.