The average train between Milan and Loreto takes 4h 58m and the fastest train takes 3h 28m. The train service runs several times per day from Milan to Loreto. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Milan and Loreto. The earliest departure is at 5:25 AM in the morning, and the last departure from Milan is at 7:50 PM which arrives into Loreto at 5:31 AM. All services require a transfer, and take on average 4h 58m. The schedules shown below are for the next available departures.

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3h 30m • 1 changeWant to know about travelling from Milan to Loreto? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Milan to Loreto. However, there are services departing from Milano Centrale station and arriving at Ancona station via Ancona station. The journey, including transfers, takes approximately 4h 58m.
Milan to Loreto train services, operated by Trenitalia Frecce, depart from Milano Centrale station.
Milan to Loreto train services, operated by Trenitalia Frecce, arrive at Ancona station.
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The distance between Milan and Loreto is 416.6 km. The road distance is 448 km.
Trenitalia Frecce operates a train from Milano Centrale to Ancona every 4 hours. Tickets cost €55–100 and the journey takes 2h 56m. Trenitalia Intercity also services this route 5 times a day.