The average train between Milan and Luxembourg takes 12h 27m and the fastest train takes 8h 39m. The train service runs several times per day from Milan to Luxembourg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Milan and Luxembourg. The earliest departure is at 11:10 AM in the morning, and the last departure from Milan is at 8:10 PM which arrives into Luxembourg at 2:15 PM. All services require a transfer at Zuerich Hb and take an average of 12h 27m. The schedules shown below are for the next available departures.



11h 14m • 3 changes



8h 39m • 3 changes
Arrives next day



18h 5m • 3 changes



11h 14m • 3 changes



8h 39m • 3 changes
Arrives next day



18h 5m • 3 changes



11h 14m • 3 changes



8h 39m • 3 changes
Arrives next day



18h 5m • 3 changes
Want to know about travelling from Milan to Luxembourg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Milan to Luxembourg. However, there are services departing from Milan station and arriving at Luxembourg station via Zuerich Hb. The journey, including transfers, takes approximately 12h 27m.
Milan to Luxembourg train services, operated by Trenitalia EuroCity, depart from Milano Centrale station.
Milan to Luxembourg train services, operated by Trenitalia EuroCity, arrive at Luxembourg station.
Book your Milan to Luxembourg train tickets online with Trenitalia EuroCity, Swiss Federal Railways (SBB CFF FFS) and 2 other operators.
The distance between Milan and Luxembourg is 515.1 km. The road distance is 685 km.
You can take a train from Milano Centrale to Luxembourg via Zuerich Hb, Zürich HB, Mulhouse, Mulhouse Ville, and Metz Ville in around 9h 44m.