The average train between Milan and Pisa Centrale takes 3h 56m and the fastest train takes 3h 48m. There is a train service every few hours from Milan to Pisa Centrale. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Milan and Pisa Centrale. The earliest departure is at 4:40 AM at night, and the last departure from Milan is at 8:40 PM which arrives into Pisa Centrale at 2:03 AM. All services require a transfer, and take on average 3h 56m. The schedules shown below are for the next available departures.

3h 53m • 1 change

3h 53m • 1 change

3h 48m • 1 change

4h 1m • 1 change

3h 48m • 1 change

3h 48m • 1 change

3h 48m • 1 change

3h 48m • 1 change

3h 48m • 1 change

3h 48m • 1 change

3h 48m • 1 change

3h 48m • 1 change

3h 48m • 1 change

3h 48m • 1 change

3h 48m • 1 change

3h 48m • 1 change
Want to know about travelling from Milan to Pisa Centrale? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Milan to Pisa Centrale. However, there are services departing from Milan station and arriving at Pisa Centrale station via Firenze S.M.N.. The journey, including transfers, takes approximately 3h 56m.
Milan to Pisa Centrale train services, operated by Trenitalia Frecce, depart from Milano Centrale station.
Milan to Pisa Centrale train services, operated by Trenitalia Frecce, arrive at Pisa Centrale station.
Book your Milan to Pisa Centrale train tickets online with Trenitalia Frecce and Trenitalia.
The distance between Milan and Pisa Centrale is 217.5 km. The road distance is 382 km.
You can take a train from Milano Centrale to Pisa Centrale via Firenze S.M.N. in around 3h 22m.