The average train between Milan and San Cassiano takes 2h 22m and the fastest train takes 1h 55m. The train service runs several times per day from Milan to San Cassiano. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Milan and San Cassiano. The earliest departure is at 6:20 AM in the morning, and the last departure from Milan is at 10:20 PM which arrives into San Cassiano at 6:39 AM. All services require a transfer, and take on average 2h 22m. The schedules shown below are for the next available departures.

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Want to know about travelling from Milan to San Cassiano? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Milan to San Cassiano. However, there are services departing from Milan station and arriving at San Cassiano station via Colico. The journey, including transfers, takes approximately 2h 22m.
Milan to San Cassiano train services, operated by Trenord, depart from Milano Centrale station.
Milan to San Cassiano train services, operated by Trenord, arrive at S. Cassiano Valchiavenna station.
Book your Milan to San Cassiano train tickets online with Trenord.
The distance between Milan and San Cassiano is 91.6 km. The road distance is 108 km.
You can take a train from Milano Centrale to S. Cassiano Valchiavenna via Colico in around 2h 33m.