The average train between Milan and Sestri Ponente takes 3h 27m and the fastest train takes 3h. The train service runs several times per day from Milan to Sestri Ponente. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 3 hours between Milan and Sestri Ponente. The earliest departure is at 5:05 AM in the morning, and the last departure from Milan is at 8:05 PM which arrives into Sestri Ponente at 11:23 PM. All services require a transfer, and take on average 3h 27m. The schedules shown below are for the next available departures.

3h 44m • 1 change

3h 24m • 1 change

3h 29m • 1 change

3h 18m • 1 change

3h • 1 change

3h 31m • 1 change

3h 11m • 1 change

3h 36m • 1 change

3h • 1 change

3h 31m • 1 change

3h 11m • 1 change

3h 36m • 1 change

3h • 1 change

3h 31m • 1 change

3h 11m • 1 change

3h 36m • 1 change

3h • 1 change

3h 31m • 1 change

3h 11m • 1 change

3h 36m • 1 change

3h 14m • 1 change

3h 36m • 1 change

3h 39m • 1 change

3h 36m • 1 change
Want to know about travelling from Milan to Sestri Ponente? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Milan to Sestri Ponente. However, there are services departing from Milan station and arriving at Sestri Ponente station via Genova P.Za Principe. The journey, including transfers, takes approximately 3h 27m.
Milan to Sestri Ponente train services, operated by Trenitalia Intercity, depart from Milano Centrale station.
Milan to Sestri Ponente train services, operated by Trenitalia Intercity, arrive at Genova P.Za Principe station.
Book your Milan to Sestri Ponente train tickets online with Trenitalia Intercity and Trenitalia.
The distance between Milan and Sestri Ponente is 118.6 km. The road distance is 145 km.
Trenitalia Intercity operates a train from Milano Centrale to Genova P.Za Principe every 30 minutes. Tickets cost €15–35 and the journey takes 1h 34m. Two other operators also service this route.