The average train between Milan and Siena Station takes 4h 35m and the fastest train takes 3h 57m. There is a train service every few hours from Milan to Siena Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Milan and Siena Station. The earliest departure is at 5:40 AM in the morning, and the last departure from Milan is at 8:40 PM which arrives into Siena Station at 7:55 AM. All services require a transfer, and take on average 4h 35m. The schedules shown below are for the next available departures.

4h • 1 change

3h 57m • 1 change

4h 5m • 1 change

3h 58m • 1 change

3h 58m • 1 change

4h • 1 change

4h • 1 change

4h 8m • 1 change

3h 58m • 1 change

4h • 1 change

4h • 1 change

4h 8m • 1 change

3h 58m • 1 change

4h • 1 change

4h • 1 change

4h 8m • 1 change
Want to know about travelling from Milan to Siena Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Milan to Siena Station. However, there are services departing from Milan station and arriving at Siena Station station via Firenze S.M.N.. The journey, including transfers, takes approximately 4h 35m.
Milan to Siena Station train services, operated by Trenitalia Frecce, depart from Milano Centrale station.
Milan to Siena Station train services, operated by Trenitalia Frecce, arrive at Siena station.
Book your Milan to Siena Station train tickets online with Trenitalia Frecce and Trenitalia.
The distance between Milan and Siena Station is 291.5 km. The road distance is 397 km.
You can take a train from Milano Centrale to Siena via Firenze S.M.N. in around 3h 49m.