The average train between Milano Centrale Station and Pisa takes 3h 45m and the fastest train takes 3h 28m. There is a train service every few hours from Milano Centrale Station to Pisa. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Milano Centrale Station and Pisa. The earliest departure is at 4:40 AM at night, and the last departure from Milano Centrale Station is at 8:00 PM which arrives into Pisa at 12:29 AM. All services require a transfer, and take on average 3h 45m. The schedules shown below are for the next available departures.

3h 48m • 1 change

3h 48m • 1 change

3h 48m • 1 change

3h 48m • 1 change

3h 33m • 1 change

3h 28m • 1 change

3h 33m • 1 change

3h 30m • 1 change

3h 33m • 1 change

3h 28m • 1 change

3h 33m • 1 change

3h 30m • 1 change

3h 33m • 1 change

3h 28m • 1 change

3h 33m • 1 change

3h 30m • 1 change
Want to know about travelling from Milano Centrale Station to Pisa? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Milano Centrale Station to Pisa. However, there are services departing from Milano Centrale Station station and arriving at Pisa station via Firenze S.M.N.. The journey, including transfers, takes approximately 3h 45m.
Milano Centrale Station to Pisa train services, operated by Trenitalia Frecce, depart from Milano Centrale station.
Milano Centrale Station to Pisa train services, operated by Trenitalia Frecce, arrive at Pisa Centrale station.
Book your Milano Centrale Station to Pisa train tickets online with Trenitalia Frecce and Trenitalia.
The distance between Milano Centrale Station and Pisa is 219.4 km. The road distance is 382 km.
You can take a train from Milano Centrale to Pisa Centrale via Firenze S.M.N. in around 3h 21m.