The average train between Milano Centrale Station and Prague takes 18h 33m and the fastest train takes 13h 57m. The train service runs several times per day from Milano Centrale Station to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Milano Centrale Station and Prague. The earliest departure is at 9:45 AM in the morning, and the last departure from Milano Centrale Station is at 5:45 PM which arrives into Prague at 3:39 PM. All services require a transfer at Verona Porta Nuova and take an average of 18h 33m. The schedules shown below are for the next available departures.




13h 57m • 4 changes
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20h 24m • 4 changes
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21h 54m • 4 changes




13h 57m • 4 changes
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20h 24m • 4 changes
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21h 54m • 4 changes




13h 57m • 4 changes
Arrives next day




20h 24m • 4 changes
Arrives next day




21h 54m • 4 changes




13h 57m • 4 changes
Arrives next day




20h 24m • 4 changes
Arrives next day




21h 54m • 4 changes




13h 57m • 4 changes
Arrives next day




20h 24m • 4 changes
Arrives next day




22h 24m • 4 changes
Want to know about travelling from Milano Centrale Station to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Milano Centrale Station to Prague. However, there are services departing from Milano Centrale Station station and arriving at Prague station via Verona Porta Nuova. The journey, including transfers, takes approximately 18h 33m.
Milano Centrale Station to Prague train services, operated by Trenitalia Frecce, depart from Milano Centrale station.
Milano Centrale Station to Prague train services, operated by Trenitalia Frecce, arrive at Praha Hlavni Nadrazi station.
Book your Milano Centrale Station to Prague train tickets online with Trenitalia Frecce, Trenitalia and 4 other operators.
The distance between Milano Centrale Station and Prague is 642.8 km. The road distance is 1,020 km.
You can take a train from Milano Centrale to Praha Hlavni Nadrazi via Verona Porta Nuova, Brennero - Brenner, Innsbruck Hauptbahnhof, and Linz/Donau Hbf in around 14h 32m.