The average train between Milton Keynes and Plymouth takes 5h 25m and the fastest train takes 4h 50m. There is a train service every few hours from Milton Keynes to Plymouth. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Milton Keynes and Plymouth. The earliest departure is at 12:15 AM at night, and the last departure from Milton Keynes is at 10:33 PM which arrives into Plymouth at 12:51 PM. All services require a transfer at London Euston and take an average of 5h 25m. The schedules shown below are for the next available departures.

10h 18m • 1 change

4h 56m • 1 change

4h 54m • 1 change

4h 54m • 1 change

10h 18m • 1 change

4h 56m • 1 change

4h 54m • 1 change

4h 54m • 1 change

10h 16m • 1 change

4h 55m • 1 change

4h 54m • 1 change

4h 54m • 1 change

5h 9m • 1 change

5h • 1 change

5h 7m • 1 change

5h 7m • 1 change
Want to know about travelling from Milton Keynes to Plymouth? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Milton Keynes to Plymouth. However, there are services departing from Milton Keynes station and arriving at Plymouth station via London Euston. The journey, including transfers, takes approximately 5h 25m.
Milton Keynes to Plymouth train services, operated by Avanti West Coast, depart from Milton Keynes Central station.
Milton Keynes to Plymouth train services, operated by Avanti West Coast, arrive at Plymouth station.
Book your Milton Keynes to Plymouth train tickets online with Avanti West Coast and Cross Country.
The distance between Milton Keynes and Plymouth is 300.2 km. The road distance is 444 km.
You can take a train from Milton Keynes Central to Plymouth via London Euston, Euston Station, Bishops Bridge Road / Little Venice, and London Paddington in around 4h 47m.