The average train between Motel One Frankfurt-Römer, Frankfurt/Main and Karlsruhe Hbf takes 1h 23m and the fastest train takes 1h 11m. There is a train service every few hours from Motel One Frankfurt-Römer, Frankfurt/Main to Karlsruhe Hbf. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Motel One Frankfurt-Römer, Frankfurt/Main and Karlsruhe Hbf. The earliest departure is at 5:39 AM in the morning, and the last departure from Motel One Frankfurt-Römer, Frankfurt/Main is at 10:42 PM which arrives into Karlsruhe Hbf at 11:59 PM. All services require a transfer at Frankfurt and take an average of 1h 23m. The schedules shown below are for the next available departures.

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1h 18m • 1 change

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Want to know about travelling from Motel One Frankfurt-Römer, Frankfurt/Main to Karlsruhe Hbf? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Motel One Frankfurt-Römer, Frankfurt/Main to Karlsruhe Hbf. However, there are services departing from Motel One Frankfurt-Römer, Frankfurt/Main station and arriving at Karlsruhe Hbf station via Karlsruhe Hauptbahnhof. The journey, including transfers, takes approximately 1h 23m.
Motel One Frankfurt-Römer, Frankfurt/Main to Karlsruhe Hbf train services, operated by Verkehrsgesellschaft Frankfurt (VGF-FFM), depart from Frankfurt station.
Motel One Frankfurt-Römer, Frankfurt/Main to Karlsruhe Hbf train services, operated by Verkehrsgesellschaft Frankfurt (VGF-FFM), arrive at Karlsruhe Hauptbahnhof station.
The distance between Motel One Frankfurt-Römer, Frankfurt/Main and Karlsruhe Hbf is 125.8 km. The road distance is 139 km.
Deutsche Bahn Intercity (DB IC) operates a train from Frankfurt to Karlsruhe Hauptbahnhof hourly. Tickets cost €25–110 and the journey takes 1h 9m. Two other operators also service this route.