Rome2Rio

Mystic to Buffalo trains

Find Transport to Buffalo

View schedule

Trip Overview

The average train between Mystic and Buffalo takes 19h 1m and the fastest train takes 11h 46m. There is at least one train per day from Mystic to Buffalo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

19h 1m
Duration
573 mi
Distance
$368
Average price
Once daily
Frequency

Mystic to Buffalo train times

Trains run once daily between Mystic and Buffalo. The earliest departure is at 10:04 AM in the morning, and the last departure from Mystic is at 8:07 PM which arrives into Buffalo at 3:32 PM. All services require a transfer, and take on average 19h 1m. The schedules shown below are for the next available departures.

Departing Friday, October 30, 2026

  •  → 

    Arrives next day

    AmtrakAmtrak23h • 1 change

Departing Saturday, October 31, 2026

  •  → 

    AmtrakAmtrak11h 46m • 1 change
  •  → 

    Arrives next day

    AmtrakAmtrak24h 5m • 1 change

Departing Sunday, November 1, 2026

  •  → 

    AmtrakAmtrak11h 46m • 1 change
  •  → 

    Arrives next day

    AmtrakAmtrak19h 25m • 1 change

Departing Monday, November 2, 2026

  •  → 

    Arrives next day

    AmtrakAmtrak19h 25m • 1 change

Departing Tuesday, November 3, 2026

  •  → 

    Arrives next day

    AmtrakAmtrak19h 25m • 1 change

Departing Wednesday, November 4, 2026

  •  → 

    Arrives next day

    AmtrakAmtrak19h 25m • 1 change

Frequently asked questions

Want to know about travelling from Mystic to Buffalo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Mystic to Buffalo.ExpandLaunch map view
  • Distance: 573.3 mi
  • Duration: 19h 1m

What companies run services between Mystic, CT, USA and Buffalo, NY, USA?

You can take a train from Mystic Station to Buffalo via Ny Moynihan Train Hall At Penn Station in around 12h 38m.

Operators