The average train between National City and Santa Ana takes 2h 43m and the fastest train takes 2h 31m. There is a train service every few hours from National City to Santa Ana. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between National City and Santa Ana. The earliest departure is at 1:13 AM at night, and the last departure from National City is at 8:28 PM which arrives into Santa Ana at 10:59 PM. All services require a transfer at America Plaza Station and take an average of 2h 43m. The schedules shown below are for the next available departures.

2h 34m • 1 change

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4h 46m • 1 change

2h 34m • 1 change

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4h 46m • 1 change

2h 34m • 1 change

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2h 34m • 1 change

4h 46m • 1 change

2h 34m • 1 change

2h 34m • 1 change

2h 34m • 1 change
Want to know about travelling from National City to Santa Ana? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from National City to Santa Ana. However, there are services departing from National City station and arriving at Santa Ana station via Santa Ana. The journey, including transfers, takes approximately 2h 43m.
National City to Santa Ana train services, operated by San Diego Metro Transit, depart from San Diego station.
National City to Santa Ana train services, operated by San Diego Metro Transit, arrive at Santa Ana station.
The distance between National City and Santa Ana is 138.6 km. The road distance is 156 km.
Amtrak operates a train from San Diego to Santa Ana hourly. Tickets cost $30–65 and the journey takes 2h 1m.