The average train between Neu-Isenburg and Heidelberg takes 1h 33m and the fastest train takes 1h 11m. There is an hourly train service from Neu-Isenburg to Heidelberg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Neu-Isenburg and Heidelberg. The earliest departure is at 12:50 AM at night, and the last departure from Neu-Isenburg is at 11:50 PM which arrives into Heidelberg at 1:32 AM. All services require a transfer at Frankfurt, Hauptbahnhof FOB and take an average of 1h 33m. The schedules shown below are for the next available departures.

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1h 23m • 1 changeWant to know about travelling from Neu-Isenburg to Heidelberg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Neu-Isenburg to Heidelberg. However, there are services departing from Frankfurt station and arriving at Heidelberg, Hauptbahnhof station via Heidelberg, Hauptbahnhof station. The journey, including transfers, takes approximately 1h 33m.
Neu-Isenburg to Heidelberg train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
Neu-Isenburg to Heidelberg train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Heidelberg, Hauptbahnhof station.
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The distance between Neu-Isenburg and Heidelberg is 71.2 km. The road distance is 81 km.
Deutsche Bahn Intercity (DB IC) operates a train from Frankfurt to Heidelberg, Hauptbahnhof hourly. Tickets cost €14–30 and the journey takes 1h 1m. Deutsche Bahn Regio (DB Regional) also services this route hourly.