The average train between Neu-Isenburg and Würzburg takes 2h 6m and the fastest train takes 1h 28m. There is a train service every few hours from Neu-Isenburg to Würzburg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Neu-Isenburg and Würzburg. The earliest departure is at 1:41 AM at night, and the last departure from Neu-Isenburg is at 7:40 PM which arrives into Würzburg at 9:46 PM. All services require a transfer at Frankfurt, Hauptbahnhof FOB and take an average of 2h 6m. The schedules shown below are for the next available departures.

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2h 25m • 1 changeWant to know about travelling from Neu-Isenburg to Würzburg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Neu-Isenburg to Würzburg. However, there are services departing from Frankfurt station and arriving at Würzburg Hbf station via Würzburg Hbf station. The journey, including transfers, takes approximately 2h 6m.
Neu-Isenburg to Würzburg train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
Neu-Isenburg to Würzburg train services, operated by Deutsche Bahn Intercity (DB IC), arrive at Würzburg Hbf station.
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The distance between Neu-Isenburg and Würzburg is 94.3 km. The road distance is 113 km.
Deutsche Bahn Intercity (DB IC) operates a train from Frankfurt to Würzburg Hbf hourly. Tickets cost €19–40 and the journey takes 1h 6m. Deutsche Bahn Regio (DB Regional) also services this route hourly.