The average train between Neu-Isenburg and Zurich takes 4h 50m and the fastest train takes 4h 26m. There is a train service every few hours from Neu-Isenburg to Zurich. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Neu-Isenburg and Zurich. The earliest departure is at 5:20 AM in the morning, and the last departure from Neu-Isenburg is at 9:50 PM which arrives into Zurich at 5:49 AM. All services require a transfer at Frankfurt and take an average of 4h 50m. The schedules shown below are for the next available departures.


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4h 26m • 2 changesWant to know about travelling from Neu-Isenburg to Zurich? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Neu-Isenburg to Zurich. However, there are services departing from Frankfurt station and arriving at Zürich HB station via Basel SBB station. The journey, including transfers, takes approximately 4h 50m.
Neu-Isenburg to Zurich train services, operated by Deutsche Bahn Intercity (DB IC), depart from Frankfurt station.
Neu-Isenburg to Zurich train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Zürich HB station.
Book your Neu-Isenburg to Zurich train tickets online with Omio.
The distance between Neu-Isenburg and Zurich is 298.4 km. The road distance is 362 km.
You can take a bus from Neu-Isenburg Isenburgzentrum Süd to Zürich HB via Frankfurt, Frankfurt, and Basel SBB in around 5h 18m.