The average train between Neuss and Prague takes 10h 52m and the fastest train takes 9h 29m. The train service runs several times per day from Neuss to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Neuss and Prague. The earliest departure is at 4:24 AM at night, and the last departure from Neuss is at 6:52 PM which arrives into Prague at 10:21 AM. All services require a transfer at Koeln Messe/Deutz and take an average of 10h 52m. The schedules shown below are for the next available departures.



9h 57m • 3 changes



9h 29m • 3 changes



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9h 57m • 3 changes



9h 29m • 3 changes



9h 29m • 3 changes



9h 29m • 3 changes



9h 57m • 3 changes



9h 29m • 3 changes



9h 29m • 3 changes



9h 29m • 3 changes



9h 57m • 3 changes



9h 29m • 3 changes



9h 29m • 3 changes



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9h 57m • 3 changes



9h 29m • 3 changes



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9h 29m • 3 changes
Want to know about travelling from Neuss to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Neuss to Prague. However, there are services departing from Neuss station and arriving at Prague station via Nürnberg Hbf. The journey, including transfers, takes approximately 10h 52m.
Neuss to Prague train services, operated by National Express, depart from Köln Messe/Deutz Bf station.
Neuss to Prague train services, operated by National Express, arrive at Praha Hlavni Nadrazi station.
Book your Neuss to Prague train tickets online with National Express, Deutsche Bahn Intercity (DB IC) and 2 other operators.
The distance between Neuss and Prague is 559 km. The road distance is 780 km.
You can take a train from Neuss Hbf to Praha Hlavni Nadrazi via Koeln Messe/Deutz, Köln Messe/Deutz Bf, Nürnberg Hbf, and Schwandorf in around 10h 33m.