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Niagara Falls to Mississippi trains

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Trip Overview

The train between Niagara Falls and Mississippi takes 2d. The train runs, on average, 6 times per week from Niagara Falls to Mississippi. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d
Duration
1,307 mi
Distance
$876
Average price
6 times a week
Frequency

Niagara Falls to Mississippi train times

Trains run 6 times a week between Niagara Falls and Mississippi. The service departs Niagara Falls at 11:50 AM in the morning, which arrives into Mississippi at 11:40:00. All services require a transfer at Buffalo Depew Station and take an average of 2d. The schedules shown below are for the next available departures.

Departing Wednesday, November 4, 2026

  •  → 

    Arrives +2 days

    VIA RailAmtrakAmtrak2d • 2 changes

Departing Thursday, November 5, 2026

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    Arrives +2 days

    VIA RailAmtrakAmtrak2d • 2 changes

Departing Friday, November 6, 2026

  •  → 

    Arrives +2 days

    VIA RailAmtrakAmtrak2d • 2 changes

Departing Saturday, November 7, 2026

  •  → 

    Arrives +2 days

    VIA RailAmtrakAmtrak2d • 2 changes

Departing Sunday, November 8, 2026

  •  → 

    Arrives +2 days

    VIA RailAmtrakAmtrak2d • 2 changes

Departing Monday, November 9, 2026

  •  → 

    Arrives +2 days

    VIA RailAmtrakAmtrak2d • 2 changes

Frequently asked questions

Want to know about travelling from Niagara Falls to Mississippi? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Niagara Falls to Mississippi.ExpandLaunch map view
  • Distance: 1,307.2 mi
  • Duration: 2d

What companies run services between Niagara Falls, NY, USA and Mississippi, USA?

You can take a train from Niagara Falls Amtrak Station to Jackson via Buffalo Depew Station and Chicago Union Station in around 28h 54m.

Operators