The average train between Nordhausen and Karlsruhe takes 5h 19m and the fastest train takes 4h 36m. There is a train service every few hours from Nordhausen to Karlsruhe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Nordhausen and Karlsruhe. The earliest departure is at 4:49 AM at night, and the last departure from Nordhausen is at 8:25 PM which arrives into Karlsruhe at 9:19 AM. All services require a transfer, and take on average 5h 19m. The schedules shown below are for the next available departures.

5h 10m • 1 change

5h 7m • 1 change

4h 37m • 1 change

4h 58m • 1 change

5h 10m • 1 change

5h 7m • 1 change

4h 37m • 1 change

4h 58m • 1 change

5h 10m • 1 change

5h 7m • 1 change

4h 37m • 1 change

4h 58m • 1 change
Want to know about travelling from Nordhausen to Karlsruhe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Nordhausen to Karlsruhe. However, there are services departing from Nordhausen station and arriving at Karlsruhe station via Kassel-Wilhelmshoehe. The journey, including transfers, takes approximately 5h 19m.
Nordhausen to Karlsruhe train services, operated by ABELLIO Rail Mitteldeutschland GmbH, depart from Nordhausen station.
Nordhausen to Karlsruhe train services, operated by ABELLIO Rail Mitteldeutschland GmbH, arrive at Karlsruhe Hauptbahnhof station.
Book your Nordhausen to Karlsruhe train tickets online with ABELLIO Rail Mitteldeutschland GmbH and Deutsche Bahn Intercity (DB IC).
The distance between Nordhausen and Karlsruhe is 325.1 km. The road distance is 448 km.
You can take a train from Nordhausen to Karlsruhe Hauptbahnhof via Kassel Bahnhof Wilhelmshöhe in around 4h 51m.