The train between Nuremberg and Prague takes 4h 44m. The train service runs several times per day from Nuremberg to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Nuremberg and Prague. The earliest departure is at 6:35 AM in the morning, and the last departure from Nuremberg is at 6:37 PM which arrives into Prague at 11:21 PM. All services require a transfer, and take on average 4h 44m. The schedules shown below are for the next available departures.

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Want to know about travelling from Nuremberg to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Nuremberg to Prague. However, there are services departing from Nuremberg station and arriving at Prague station via Cheb. The journey, including transfers, takes approximately 4h 44m.
Nuremberg to Prague train services, operated by Deutsche Bahn Regio (DB Regional), depart from Nürnberg Hbf station.
Nuremberg to Prague train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Praha Hlavni Nadrazi station.
Book your Nuremberg to Prague train tickets online with Deutsche Bahn Regio (DB Regional) and České dráhy (ČD).
The distance between Nuremberg and Prague is 250.2 km. The road distance is 356 km.
You can take a train from Nürnberg Hbf to Praha Hlavni Nadrazi via Cheb in around 5h 14m.