The average train between Nyon and Florence takes 14h 59m and the fastest train takes 8h 56m. The train service runs several times per day from Nyon to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Nyon and Florence. The earliest departure is at 5:39 AM in the morning, and the last departure from Nyon is at 10:39 PM which arrives into Florence at 12:35 PM. All services require a transfer at Brig and take an average of 14h 59m. The schedules shown below are for the next available departures.



8h 56m • 3 changes



9h 56m • 3 changes



8h 56m • 3 changes
Arrives next day



17h 56m • 3 changes
Arrives next day



17h 56m • 3 changes
Arrives next day



16h 56m • 3 changes
Arrives next day



17h 56m • 3 changes
Arrives next day



16h 56m • 3 changes
Want to know about travelling from Nyon to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Nyon to Florence. However, there are services departing from Nyon station and arriving at Florence station via Brig. The journey, including transfers, takes approximately 14h 59m.
Nyon to Florence train services, operated by Swiss Federal Railways (SBB CFF FFS), depart from Nyon station.
Nyon to Florence train services, operated by Swiss Federal Railways (SBB CFF FFS), arrive at Firenze Santa Maria Novella station.
Book your Nyon to Florence train tickets online with Swiss Federal Railways (SBB CFF FFS), BLS AG and 2 other operators.
The distance between Nyon and Florence is 488.1 km. The road distance is 645 km.
You can take a train from Nyon to Firenze Santa Maria Novella via Brig, Domodossola, and Milano Rogoredo in around 9h 15m.