The average train between Offenbach am Main and Karlsruhe takes 1h 33m and the fastest train takes 1h 22m. There is a train service every few hours from Offenbach am Main to Karlsruhe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Offenbach am Main and Karlsruhe. The earliest departure is at 1:31 AM at night, and the last departure from Offenbach am Main is at 10:31 PM which arrives into Karlsruhe at 11:59 PM. All services require a transfer, and take on average 1h 33m. The schedules shown below are for the next available departures.

1h 28m • 1 change

1h 58m • 1 change

1h 22m • 1 change

1h 28m • 1 change

1h 28m • 1 change

1h 58m • 1 change

1h 22m • 1 change

1h 28m • 1 change

4h 31m • 1 change

2h 3m • 1 change

1h 22m • 1 change

1h 22m • 1 change
Want to know about travelling from Offenbach am Main to Karlsruhe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Offenbach am Main to Karlsruhe. However, there are services departing from Offenbach am Main station and arriving at Karlsruhe station via Karlsruhe Hauptbahnhof. The journey, including transfers, takes approximately 1h 33m.
Offenbach am Main to Karlsruhe train services, operated by Deutsche Bahn Regio (DB Regional), depart from Frankfurt station.
Offenbach am Main to Karlsruhe train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Karlsruhe Hauptbahnhof station.
Book your Offenbach am Main to Karlsruhe train tickets online with Deutsche Bahn Regio (DB Regional), Deutsche Bahn Intercity (DB IC) and Österreichische Bundesbahnen.
The distance between Offenbach am Main and Karlsruhe is 124.6 km. The road distance is 148 km.
Deutsche Bahn Intercity (DB IC) operates a train from Frankfurt to Karlsruhe Hauptbahnhof hourly. Tickets cost €25–110 and the journey takes 1h 9m. Österreichische Bundesbahnen also services this route twice a week.