The average train between Oppenheim and Karlsruhe takes 1h 47m and the fastest train takes 1h 22m. There is a train service every few hours from Oppenheim to Karlsruhe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Oppenheim and Karlsruhe. The earliest departure is at 5:35 AM in the morning, and the last departure from Oppenheim is at 11:29 PM which arrives into Karlsruhe at 1:48 AM. All services require a transfer, and take on average 1h 47m. The schedules shown below are for the next available departures.

1h 24m • 1 change

1h 46m • 1 change

1h 42m • 1 change

1h 25m • 1 change

1h 24m • 1 change

1h 46m • 1 change

1h 42m • 1 change

1h 25m • 1 change

1h 24m • 1 change

1h 46m • 1 change

1h 42m • 1 change

1h 25m • 1 change
Want to know about travelling from Oppenheim to Karlsruhe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Oppenheim to Karlsruhe. However, there are services departing from Oppenheim station and arriving at Karlsruhe station via Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 1h 47m.
Oppenheim to Karlsruhe train services, operated by Deutsche Bahn Regio (DB Regional), depart from Oppenheim, Bahnhof station.
Oppenheim to Karlsruhe train services, operated by Deutsche Bahn Regio (DB Regional), arrive at Karlsruhe Hauptbahnhof station.
Book your Oppenheim to Karlsruhe train tickets online with Deutsche Bahn Regio (DB Regional), Deutsche Bahn Intercity (DB IC) and Süwex.
The distance between Oppenheim and Karlsruhe is 93.8 km. The road distance is 109 km.
You can take a train from Oppenheim, Bahnhof to Karlsruhe Hauptbahnhof via Mannheim, Hauptbahnhof in around 1h 32m.