The average train between Oppenheim and Karlsruhe takes 1h 45m and the fastest train takes 1h 20m. There is an hourly train service from Oppenheim to Karlsruhe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Oppenheim and Karlsruhe. The earliest departure is at 1:59 AM at night, and the last departure from Oppenheim is at 11:29 PM which arrives into Karlsruhe at 1:48 AM. All services require a transfer, and take on average 1h 45m. The schedules shown below are for the next available departures.

1h 33m • 1 changeArrives next day

1h 40m • 1 changeArrives next day

2h 19m • 1 change
2h • 1 change
2h 4m • 1 change
1h 42m • 1 change
1h 25m • 1 change
1h 24m • 1 change
1h 46m • 1 change
1h 42m • 1 change
1h 25m • 1 changeWant to know about travelling from Oppenheim to Karlsruhe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Oppenheim to Karlsruhe. However, there are services departing from Oppenheim station and arriving at Karlsruhe station via Mannheim, Hauptbahnhof. The journey, including transfers, takes approximately 1h 45m.
Oppenheim to Karlsruhe train services, operated by Süwex, depart from Oppenheim, Bahnhof station.
Oppenheim to Karlsruhe train services, operated by Süwex, arrive at Karlsruhe Hauptbahnhof station.
Book your Oppenheim to Karlsruhe train tickets online with Süwex, Deutsche Bahn Intercity (DB IC) and 2 other operators.
The distance between Oppenheim and Karlsruhe is 93.8 km. The road distance is 109 km.
You can take a train from Oppenheim, Bahnhof to Karlsruhe Hauptbahnhof via Mannheim, Hauptbahnhof in around 1h 35m.