The average train between Orvieto and Brindisi takes 8h 48m and the fastest train takes 7h 58m. The train service runs several times per day from Orvieto to Brindisi. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Orvieto and Brindisi. The earliest departure is at 5:54 AM in the morning, and the last departure from Orvieto is at 11:25 PM which arrives into Brindisi at 1:57 PM. All services require a transfer, and take on average 8h 48m. The schedules shown below are for the next available departures.

8h 3m • 1 change

8h 34m • 1 change

8h 26m • 1 change

7h 58m • 1 change
Want to know about travelling from Orvieto to Brindisi? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Orvieto to Brindisi. However, there are services departing from Orvieto station and arriving at Brindisi station via Roma Termini. The journey, including transfers, takes approximately 8h 48m.
Orvieto to Brindisi train services, operated by Trenitalia, depart from Orvieto station.
Orvieto to Brindisi train services, operated by Trenitalia, arrive at Brindisi station.
Book your Orvieto to Brindisi train tickets online with Trenitalia, Trenitalia Frecce and Trenitalia Intercity.
The distance between Orvieto and Brindisi is 536.3 km. The road distance is 698 km.
You can take a train from Orvieto to Brindisi via Roma Termini in around 8h.