The average train between Osnabrück and Prague takes 10h 46m and the fastest train takes 8h 21m. The train service runs several times per day from Osnabrück to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Osnabrück and Prague. The earliest departure is at 8:54 AM in the morning, and the last departure from Osnabrück is at 6:54 PM which arrives into Prague at 10:57 AM. All services require a transfer, and take on average 10h 46m. The schedules shown below are for the next available departures.

8h 21m • 1 change

8h 21m • 1 change
Arrives next day

16h 3m • 1 change

8h 21m • 1 change

8h 21m • 1 change
Arrives next day

16h 3m • 1 change

8h 21m • 1 change

8h 21m • 1 change
Arrives next day

16h 3m • 1 change

8h 21m • 1 change

8h 21m • 1 change
Arrives next day

16h 3m • 1 change
Want to know about travelling from Osnabrück to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Osnabrück to Prague. However, there are services departing from Osnabrück station and arriving at Prague station via Berlin Hbf. The journey, including transfers, takes approximately 10h 46m.
Osnabrück to Prague train services, operated by Nederlandse Spoorwegen (NS), depart from Osnabrueck Hbf station.
Osnabrück to Prague train services, operated by Nederlandse Spoorwegen (NS), arrive at Praha-Holesovice station.
Book your Osnabrück to Prague train tickets online with Nederlandse Spoorwegen (NS) and Danish Railways (DSB).
The distance between Osnabrück and Prague is 505.9 km. The road distance is 752 km.
You can take a train from Osnabrueck Hbf to Praha-Holesovice via Berlin Hbf in around 7h 38m.