The average train between Otranto and Mesagne takes 6h 1m and the fastest train takes 2h 49m. The train service runs several times per day from Otranto to Mesagne. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 3 times a day between Otranto and Mesagne. The earliest departure is at 10:50 AM in the morning, and the last departure from Otranto is at 7:53 PM which arrives into Mesagne at 11:15 AM. All services require a transfer at Maglie and take an average of 6h 1m. The schedules shown below are for the next available departures.



3h 26m • 3 changes



2h 49m • 3 changes



4h 21m • 3 changes
Arrives next day



15h 22m • 3 changes



3h 26m • 3 changes



2h 49m • 3 changes



4h 21m • 3 changes
Arrives next day



15h 22m • 3 changes
Want to know about travelling from Otranto to Mesagne? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Otranto to Mesagne. However, there are services departing from Otranto station and arriving at Mesagne station via Maglie. The journey, including transfers, takes approximately 6h 1m.
Otranto to Mesagne train services, operated by Ferrovie del Sud Est e Servizi Automobilistici S.r.l., depart from Otranto station.
Otranto to Mesagne train services, operated by Ferrovie del Sud Est e Servizi Automobilistici S.r.l., arrive at Lecce station.
Book your Otranto to Mesagne train tickets online with Ferrovie del Sud Est e Servizi Automobilistici S.r.l. and Trenitalia.
The distance between Otranto and Mesagne is 73.4 km. The road distance is 101 km.
You can take a train from Otranto to Mesagne via Maglie, Lecce, and Brindisi in around 4h 5m.