The average train between Padre Pio and Rome takes 5h 10m and the fastest train takes 4h 12m. There is a train service every few hours from Padre Pio to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Padre Pio and Rome. The earliest departure is at 5:07 AM in the morning, and the last departure from Padre Pio is at 11:27 PM which arrives into Rome at 9:25 AM. All services require a transfer at Monza and take an average of 5h 10m. The schedules shown below are for the next available departures.

5h 8m • 1 change

5h 18m • 1 change

5h • 1 change

4h 12m • 1 change

5h 8m • 1 change

4h 48m • 1 change

4h 43m • 1 change

4h 50m • 1 change

5h 8m • 1 change

4h 48m • 1 change

4h 43m • 1 change

4h 50m • 1 change

5h 8m • 1 change

4h 48m • 1 change

4h 43m • 1 change

4h 48m • 1 change
Want to know about travelling from Padre Pio to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Padre Pio to Rome. However, there are services departing from Padre Pio station and arriving at Rome station via Roma Termini. The journey, including transfers, takes approximately 5h 10m.
Padre Pio to Rome train services, operated by Trenord, depart from Milano Centrale station.
Padre Pio to Rome train services, operated by Trenord, arrive at Roma Termini station.
The distance between Padre Pio and Rome is 484.4 km. The road distance is 573 km.
Trenitalia Frecce operates a train from Milano Centrale to Roma Termini every 20 minutes. Tickets cost €80–170 and the journey takes 3h 4m. ItaloTreno also services this route once daily.