The average train between Palermo and Alessandria takes 26h 19m and the fastest train takes 25h 6m. The train service runs several times per day from Palermo to Alessandria. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Palermo and Alessandria. The earliest departure is at 7:05 AM in the morning, and the last departure from Palermo is at 10:15 AM which arrives into Alessandria at 12:44 PM. All services require a transfer at Roma Termini and take an average of 26h 19m. The schedules shown below are for the next available departures.
Arrives next day



25h 6m • 3 changes
Arrives next day



27h 56m • 3 changes
Arrives next day



25h 6m • 3 changes
Arrives next day



27h 56m • 3 changes
Arrives next day



25h 6m • 3 changes
Arrives next day



27h 56m • 3 changes
Want to know about travelling from Palermo to Alessandria? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Palermo to Alessandria. However, there are services departing from Palermo station and arriving at Alessandria station via Roma Termini. The journey, including transfers, takes approximately 26h 19m.
Palermo to Alessandria train services, operated by Trenitalia Intercity, depart from Palermo Centrale station.
Palermo to Alessandria train services, operated by Trenitalia Intercity, arrive at Tortona station.
Book your Palermo to Alessandria train tickets online with Trenitalia Intercity, Trenitalia Frecce and 2 other operators.
The distance between Palermo and Alessandria is 849.7 km. The road distance is 1,515 km.
You can take a train from Palermo Centrale to Alessandria via Roma Termini, Milano Rogoredo, and Tortona in around 17h 6m.