The average train between Palermo and Alessandria takes 25h 52m and the fastest train takes 23h 39m. The train service runs several times per day from Palermo to Alessandria. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Palermo and Alessandria. The earliest departure is at 7:05 AM in the morning, and the last departure from Palermo is at 10:15 AM which arrives into Alessandria at 2:41 PM. All services require a transfer at Roma Termini and take an average of 25h 52m. The schedules shown below are for the next available departures.
Arrives next day


23h 39m • 2 changes
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26h 29m • 2 changes
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23h 39m • 2 changes
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28h 26m • 2 changes
Arrives next day


23h 39m • 2 changes
Arrives next day


28h 26m • 2 changes
Arrives next day


23h 39m • 2 changes
Arrives next day


28h 26m • 2 changes
Want to know about travelling from Palermo to Alessandria? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Palermo to Alessandria. However, there are services departing from Palermo station and arriving at Alessandria station via Roma Termini. The journey, including transfers, takes approximately 25h 52m.
Palermo to Alessandria train services, operated by Trenitalia Intercity, depart from Palermo Centrale station.
Palermo to Alessandria train services, operated by Trenitalia Intercity, arrive at Alessandria station.
Book your Palermo to Alessandria train tickets online with Trenitalia Intercity, Trenitalia Frecce and Trenord.
The distance between Palermo and Alessandria is 849.7 km. The road distance is 1,515 km.
You can take a train from Palermo Centrale to Alessandria via Roma Termini and Milan Rogoredo in around 17h 28m.