The average train between Palermo and Brescia takes 24h 33m and the fastest train takes 23h 56m. The train service runs several times per day from Palermo to Brescia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run twice daily between Palermo and Brescia. The earliest departure is at 7:05 AM in the morning, and the last departure from Palermo is at 10:15 AM which arrives into Brescia at 10:11 AM. All services require a transfer at Roma Termini and take an average of 24h 33m. The schedules shown below are for the next available departures.
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25h 6m • 2 changesArrives next day


23h 56m • 2 changesArrives next day


25h 6m • 2 changesArrives next day


23h 56m • 2 changesArrives next day


25h 6m • 2 changesArrives next day


23h 56m • 2 changesWant to know about travelling from Palermo to Brescia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Palermo to Brescia. However, there are services departing from Palermo station and arriving at Brescia station via Roma Termini. The journey, including transfers, takes approximately 24h 33m.
Palermo to Brescia train services, operated by Trenitalia Intercity, depart from Palermo Centrale station.
Palermo to Brescia train services, operated by Trenitalia Intercity, arrive at Brescia station.
Book your Palermo to Brescia train tickets online with Trenitalia Intercity and ItaloTreno.
The distance between Palermo and Brescia is 862.7 km. The road distance is 1,528 km.
You can take a train from Palermo Centrale to Brescia via Roma Termini and Milano Centrale in around 15h 53m.