The average train between Palermo and Isola Ortigia takes 4h 27m and the fastest train takes 4h 1m. The train service runs several times per day from Palermo to Isola Ortigia. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Palermo and Isola Ortigia. The earliest departure is at 7:31 AM in the morning, and the last departure from Palermo is at 5:31 PM which arrives into Isola Ortigia at 9:32 PM. All services require a transfer, and take on average 4h 27m. The schedules shown below are for the next available departures.

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4h 29m • 1 change

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4h 29m • 1 change
Want to know about travelling from Palermo to Isola Ortigia? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Palermo to Isola Ortigia. However, there are services departing from Palermo station and arriving at Isola Ortigia station via Catania Aeroporto Fontanarossa. The journey, including transfers, takes approximately 4h 27m.
Palermo to Isola Ortigia train services, operated by Trenitalia, depart from Palermo Centrale station.
Palermo to Isola Ortigia train services, operated by Trenitalia, arrive at Siracusa station.
The distance between Palermo and Isola Ortigia is 209.7 km. The road distance is 313 km.
You can take a train from Palermo Centrale to Siracusa via Catania Aeroporto Fontanarossa in around 4h 23m.