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Palermo to Madrid trains

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Trip Overview

The train between Palermo and Madrid takes 39h 37m. The train runs, on average, 6 times per week from Palermo to Madrid. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

39h 37m
Duration
3,154 km
Distance
€436
Average price
6 times a week
Frequency

Palermo to Madrid train times

Trains run 6 times a week between Palermo and Madrid. The service departs Palermo at 7:05 AM in the morning, which arrives into Madrid at 22:42:00. All services require a transfer at Roma Termini and take an average of 39h 37m. The schedules shown below are for the next available departures.

Departing Monday, November 2, 2026

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    Arrives next day

    Trenitalia IntercityItaloTrenoTrenitaliaRenfe Viajerosiryo39h 37m • 4 changes

Departing Tuesday, November 3, 2026

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    Arrives next day

    Trenitalia IntercityItaloTrenoTrenitaliaRenfe Viajerosiryo39h 37m • 4 changes

Departing Wednesday, November 4, 2026

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    Arrives next day

    Trenitalia IntercityItaloTrenoTrenitaliaRenfe Viajerosiryo39h 37m • 4 changes

Departing Thursday, November 5, 2026

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    Arrives next day

    Trenitalia IntercityItaloTrenoTrenitaliaRenfe Viajerosiryo39h 37m • 4 changes

Departing Friday, November 6, 2026

  •  → 

    Arrives next day

    Trenitalia IntercityItaloTrenoTrenitaliaRenfe Viajerosiryo39h 37m • 4 changes

Departing Saturday, November 7, 2026

  •  → 

    Arrives next day

    Trenitalia IntercityItaloTrenoTrenitaliaRenfe Viajerosiryo39h 37m • 4 changes

Frequently asked questions

Want to know about travelling from Palermo to Madrid? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Palermo to Madrid.ExpandLaunch map view
  • Distance: 3,153.7 km
  • Duration: 39h 37m

What companies run services between Palermo, Italy and Madrid, Spain?

You can take a train from Palermo Centrale to Madrid-Puerta de Atocha-Almudena Grandes via Roma Termini, Milano Centrale, Lyon Part Dieu, and Barcelona-Sants in around 29h 24m.

Operators