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Palermo to Sesto Calende trains

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Trip Overview

The average train between Palermo and Sesto Calende takes 25h 15m and the fastest train takes 23h 59m. The train service runs several times per day from Palermo to Sesto Calende. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

25h 15m
Duration
1,486 km
Distance
€217
Average price
Twice daily
Frequency

Palermo to Sesto Calende train times

Trains run twice daily between Palermo and Sesto Calende. The earliest departure is at 7:05 AM in the morning, and the last departure from Palermo is at 10:15 AM which arrives into Sesto Calende at 12:32 PM. All services require a transfer at Roma Termini and take an average of 25h 15m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

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    Arrives next day

    Trenitalia IntercityItaloTrenoTrenitalia23h 59m • 2 changes
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    Arrives next day

    Trenitalia IntercityItaloTrenoTrenitalia26h 17m • 2 changes

Departing Thursday, November 12, 2026

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    Arrives next day

    Trenitalia IntercityItaloTrenoTrenitalia23h 59m • 2 changes
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    Arrives next day

    Trenitalia IntercityItaloTrenoTrenitalia26h 17m • 2 changes

Departing Friday, November 13, 2026

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    Arrives next day

    Trenitalia IntercityItaloTrenoTrenitalia23h 59m • 2 changes
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    Arrives next day

    Trenitalia IntercityItaloTrenoTrenitalia26h 17m • 2 changes

Departing Saturday, November 14, 2026

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    Arrives next day

    Trenitalia IntercityItaloTrenoTrenitalia25h 27m • 2 changes
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    Arrives next day

    Trenitalia IntercityItaloTrenoTrenitalia26h 17m • 2 changes

Departing Sunday, November 15, 2026

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    Arrives next day

    Trenitalia IntercityItaloTrenoTrenitalia23h 59m • 2 changes
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    Arrives next day

    Trenitalia IntercityItaloTrenoTrenitalia26h 17m • 2 changes

Departing Monday, November 16, 2026

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    Arrives next day

    Trenitalia IntercityItaloTrenoTrenitalia23h 59m • 2 changes
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    Arrives next day

    Trenitalia IntercityTrenitalia FrecceTrenitalia26h 17m • 2 changes

Frequently asked questions

Want to know about travelling from Palermo to Sesto Calende? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Palermo to Sesto Calende.ExpandLaunch map view
  • Distance: 1,485.9 km
  • Duration: 25h 15m

What companies run services between Palermo, Italy and Sesto Calende, Italy?

You can take a train from Palermo Centrale to Sesto Calende via Roma Termini and Rho-Fiera Milano in around 16h 42m.

Operators