The average train between Penn Station and 22ND STREET station takes 3h 26m and the fastest train takes 2h 56m. There is an hourly train service from Penn Station to 22ND STREET station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Penn Station and 22ND STREET station. The earliest departure is at 5:22 AM in the morning, and the last departure from Penn Station is at 10:51 PM which arrives into 22ND STREET station at 5:48 AM. All services require a transfer at Baltimore Penn Station and take an average of 3h 26m. The schedules shown below are for the next available departures.
Arrives next day


3h 33m • 2 changes
Arrives next day


6h 57m • 2 changes


2h 59m • 2 changes


3h 12m • 2 changes


3h 2m • 2 changes


3h 32m • 2 changes


2h 59m • 2 changes


3h 12m • 2 changes


3h 2m • 2 changes


3h 32m • 2 changes
Want to know about travelling from Penn Station to 22ND STREET station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Penn Station to 22ND STREET station station. However, there are services departing from Penn Station station and arriving at 22ND STREET station via Newark Penn Station station. The journey, including transfers, takes approximately 3h 26m.
Penn Station to 22ND STREET station train services, operated by Amtrak, depart from Baltimore Penn Station.
Penn Station to 22ND STREET station train services, operated by Amtrak, arrive at Newark Penn Station.
The distance between Penn Station and 22ND STREET station is 260.8 km. The road distance is 303 km.
Amtrak Acela operates a train from Baltimore Penn Station to Newark Penn Station every 3 hours. Tickets cost $40–700 and the journey takes 2h 10m. Amtrak also services this route hourly.