The average train between Penrith and Holyhead takes 4h 41m and the fastest train takes 4h 8m. The train service runs several times per day from Penrith to Holyhead. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Penrith and Holyhead. The earliest departure is at 5:59 AM in the morning, and the last departure from Penrith is at 9:41 PM which arrives into Holyhead at 2:09 AM. All services require a transfer, and take on average 4h 41m. The schedules shown below are for the next available departures.

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4h 36m • 1 changeWant to know about travelling from Penrith to Holyhead? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Penrith to Holyhead. However, there are services departing from Penrith North Lakes station and arriving at Holyhead station via Warrington Bank Quay station. The journey, including transfers, takes approximately 4h 41m.
Penrith to Holyhead train services, operated by Avanti West Coast, depart from Penrith North Lakes station.
Penrith to Holyhead train services, operated by Transport for Wales, arrive at Holyhead station.
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The distance between Penrith and Holyhead is 194.3 km. The road distance is 321 km.
You can take a train from Penrith North Lakes to Holyhead via Warrington Bank Quay in around 4h 29m.