The average train between Penzance and Uxbridge takes 5h 51m and the fastest train takes 5h 27m. The train service runs several times per day from Penzance to Uxbridge. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 2 hours between Penzance and Uxbridge. The earliest departure is at 5:03 AM in the morning, and the last departure from Penzance is at 9:45 PM which arrives into Uxbridge at 4:41 AM. All services require a transfer, and take on average 5h 51m. The schedules shown below are for the next available departures.

5h 27m • 1 change

5h 55m • 1 change

5h 49m • 1 change

5h 44m • 1 change

5h 27m • 1 change

5h 55m • 1 change

5h 49m • 1 change

5h 44m • 1 change

5h 48m • 1 change

5h 50m • 1 change

5h 45m • 1 change

5h 49m • 1 change

5h 50m • 1 change

5h 51m • 1 change

5h 48m • 1 change

5h 42m • 1 change

5h 27m • 1 change

5h 55m • 1 change

5h 49m • 1 change

5h 44m • 1 change
Want to know about travelling from Penzance to Uxbridge? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Penzance to Uxbridge. However, there are services departing from Penzance station and arriving at Uxbridge station via Reading. The journey, including transfers, takes approximately 5h 51m.
Penzance to Uxbridge train services, operated by Great Western Railway (GWR), depart from Penzance station.
Penzance to Uxbridge train services, operated by Great Western Railway (GWR), arrive at Reading station.
Book your Penzance to Uxbridge train tickets online with Great Western Railway (GWR) and Elizabeth Line (TfL).
The distance between Penzance and Uxbridge is 388.9 km. The road distance is 466 km.
Great Western Railway (GWR) operates a train from Penzance to Reading every 2 hours. Tickets cost £120–230 and the journey takes 4h 43m.