The average train between Perugia and Cassino takes 5h 21m and the fastest train takes 3h 52m. The train service runs several times per day from Perugia to Cassino. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run 5 times a day between Perugia and Cassino. The earliest departure is at 5:52 AM in the morning, and the last departure from Perugia is at 5:50 PM which arrives into Cassino at 11:40 PM. All services require a transfer, and take on average 5h 21m. The schedules shown below are for the next available departures.

5h 27m • 1 change

5h 18m • 1 change

4h 42m • 1 change

4h 16m • 1 change

3h 52m • 1 change

5h 52m • 1 change

5h 58m • 1 change

4h 50m • 1 change

4h 40m • 1 change

5h 52m • 1 change

5h 58m • 1 change

4h 50m • 1 change

4h 40m • 1 change

5h 52m • 1 change

5h 58m • 1 change

4h 50m • 1 change

4h 40m • 1 change

5h 52m • 1 change

5h 58m • 1 change

4h 50m • 1 change

4h 40m • 1 change

5h 52m • 1 change

5h 58m • 1 change

4h 50m • 1 change
Want to know about travelling from Perugia to Cassino? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Perugia to Cassino. However, there are services departing from Perugia station and arriving at Cassino station via Roma Termini. The journey, including transfers, takes approximately 5h 21m.
Perugia to Cassino train services, operated by Trenitalia, depart from Perugia station.
Perugia to Cassino train services, operated by Trenitalia, arrive at Cassino station.
Book your Perugia to Cassino train tickets online with Trenitalia, Trenitalia Frecce and Trenitalia Intercity.
The distance between Perugia and Cassino is 216.1 km. The road distance is 326 km.
You can take a train from Perugia to Cassino via Roma Termini in around 5h 31m.