Rome2Rio

Piazza del Duomo to Rome trains

Find Transport to Rome

View schedule
QR code to download the Rome2Rio app

Download the Rome2Rio travel app

Scan QR code with your phone to download the app

Download on the App StoreGet it on Google Play

Trip Overview

The average train between Piazza del Duomo and Rome takes 3h 49m and the fastest train takes 3h 30m. There is a train service every few hours from Piazza del Duomo to Rome. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 49m
Duration
584 km
Distance
€82
Average price
Hourly
Frequency

Piazza del Duomo to Rome train times

Trains run hourly between Piazza del Duomo and Rome. The earliest departure is at 5:20 AM in the morning, and the last departure from Piazza del Duomo is at 7:10 PM which arrives into Rome at 11:24 PM. All services require a transfer at via grossi and take an average of 3h 49m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    ATMItaloTreno4h 17m • 1 change

Departing Thursday, November 12, 2026

  •  → 

    ATMItaloTreno3h 59m • 1 change
  •  → 

    ATMItaloTreno3h 44m • 1 change
  •  → 

    ATMItaloTreno3h 41m • 1 change
  •  → 

    ATMItaloTreno3h 30m • 1 change
  • Show more

Departing Friday, November 13, 2026

  •  → 

    ATMItaloTreno3h 59m • 1 change
  •  → 

    ATMItaloTreno3h 44m • 1 change
  •  → 

    ATMItaloTreno3h 41m • 1 change
  •  → 

    ATMItaloTreno3h 30m • 1 change
  • Show more

Departing Saturday, November 14, 2026

  •  → 

    ATMItaloTreno3h 59m • 1 change
  •  → 

    ATMItaloTreno3h 44m • 1 change
  •  → 

    ATMItaloTreno3h 44m • 1 change
  •  → 

    ATMItaloTreno3h 34m • 1 change
  • Show more

Departing Sunday, November 15, 2026

  •  → 

    ATMItaloTreno3h 59m • 1 change
  •  → 

    ATMItaloTreno3h 44m • 1 change
  •  → 

    ATMItaloTreno3h 44m • 1 change
  •  → 

    ATMItaloTreno3h 31m • 1 change
  • Show more

Departing Monday, November 16, 2026

  •  → 

    ATMItaloTreno3h 59m • 1 change
  •  → 

    ATMItaloTreno3h 44m • 1 change
  •  → 

    ATMItaloTreno3h 41m • 1 change
  •  → 

    ATMItaloTreno3h 30m • 1 change
  • Show more

Departing Tuesday, November 17, 2026

  •  → 

    ATMItaloTreno3h 59m • 1 change
  •  → 

    ATMItaloTreno3h 44m • 1 change
  •  → 

    ATMItaloTreno3h 41m • 1 change
  •  → 

    ATMItaloTreno3h 30m • 1 change
  • Show more

Frequently asked questions

Want to know about travelling from Piazza del Duomo to Rome? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Piazza del Duomo to Rome.ExpandLaunch map view
  • Distance: 584.4 km
  • Duration: 3h 49m

What companies run services between Piazza del Duomo, Lombardy, Italy and Rome, Italy?

ItaloTreno operates a train from Milano Centrale to Roma Termini every 30 minutes. Tickets cost €65–110 and the journey takes 3h 5m.

Operators