The average train between Piazza del Duomo and Venice takes 3h 9m and the fastest train takes 2h 58m. The train service runs several times per day from Piazza del Duomo to Venice. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run every 4 hours between Piazza del Duomo and Venice. The earliest departure is at 8:32 AM in the morning, and the last departure from Piazza del Duomo is at 8:28 PM which arrives into Venice at 11:47 PM. All services require a transfer at Duomo M3 and take an average of 3h 9m. The schedules shown below are for the next available departures.

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Want to know about travelling from Piazza del Duomo to Venice? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Piazza del Duomo to Venice. However, there are services departing from Piazza del Duomo station and arriving at Venice station via Venezia S. Lucia. The journey, including transfers, takes approximately 3h 9m.
Piazza del Duomo to Venice train services, operated by ATM, depart from Milano Centrale station.
Piazza del Duomo to Venice train services, operated by ATM, arrive at Venezia S. Lucia station.
The distance between Piazza del Duomo and Venice is 245.2 km. The road distance is 269 km.
Trenitalia Frecce operates a train from Milano Centrale to Venezia S. Lucia hourly. Tickets cost €40–80 and the journey takes 2h 27m. Trenitalia EuroCity also services this route 4 times a week.