The average train between Piazza del Popolo and Milan takes 3h 41m and the fastest train takes 3h 14m. There is a train service every few hours from Piazza del Popolo to Milan. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Piazza del Popolo and Milan. The earliest departure is at 6:17 AM in the morning, and the last departure from Piazza del Popolo is at 11:43 PM which arrives into Milan at 9:20 AM. All services require a transfer at Flaminio and take an average of 3h 41m. The schedules shown below are for the next available departures.

3h 27m • 1 change

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3h 20m • 1 change

3h 27m • 1 change

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3h 24m • 1 change

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3h 27m • 1 change

3h 18m • 1 change

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3h 20m • 1 change
Want to know about travelling from Piazza del Popolo to Milan? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Piazza del Popolo to Milan. However, there are services departing from Piazza del Popolo station and arriving at Milan station via Milano Centrale. The journey, including transfers, takes approximately 3h 41m.
Piazza del Popolo to Milan train services, operated by ATAC S.p.A. Azienda per la mobilità, depart from Roma Termini station.
Piazza del Popolo to Milan train services, operated by ATAC S.p.A. Azienda per la mobilità, arrive at Milano Centrale station.
The distance between Piazza del Popolo and Milan is 475.3 km. The road distance is 584 km.
ItaloTreno operates a train from Roma Termini to Milano Centrale every 30 minutes. Tickets cost €70–150 and the journey takes 3h 5m.