The average train between Pisa Centrale and Vatican Museums takes 3h 19m and the fastest train takes 2h 52m. There is an hourly train service from Pisa Centrale to Vatican Museums. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Trains run hourly between Pisa Centrale and Vatican Museums. The earliest departure is at 4:15 AM at night, and the last departure from Pisa Centrale is at 8:42 PM which arrives into Vatican Museums at 6:01 AM. All services require a transfer at Firenze S.M.N. and take an average of 3h 19m. The schedules shown below are for the next available departures.


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3h 2m • 2 changesWant to know about travelling from Pisa Centrale to Vatican Museums? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct train from Pisa Centrale to Vatican Museums. However, there are services departing from Pisa Centrale station and arriving at Roma Termini station via Firenze S.M.N. station. The journey, including transfers, takes approximately 3h 19m.
Pisa Centrale to Vatican Museums train services, operated by Trenitalia, depart from Pisa Centrale station.
Pisa Centrale to Vatican Museums train services, operated by Trenitalia Frecce, arrive at Roma Termini station.
The distance between Pisa Centrale and Vatican Museums is 261.4 km. The road distance is 324 km.
You can take a train from Pisa Centrale to Vatican Museums via Firenze S.M.N., Rome Termini, Termini, and Ottaviano in around 3h 31m.