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Pisa Centrale to Vatican Museums trains

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Trip Overview

The average train between Pisa Centrale and Vatican Museums takes 5h 2m and the fastest train takes 2h 44m. There is at least one train per day from Pisa Centrale to Vatican Museums. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 2m
Duration
345 km
Distance
€56
Average price
Once daily
Frequency

Pisa Centrale to Vatican Museums train times

Trains run once daily between Pisa Centrale and Vatican Museums. The earliest departure is at 7:33 AM in the morning, and the last departure from Pisa Centrale is at 8:38 PM which arrives into Vatican Museums at 6:40 AM. All services require a transfer at Roma Tiburtina and take an average of 5h 2m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    Arrives next day

    Trenitalia FrecceTrenitalia10h 2m • 1 change

Departing Thursday, November 12, 2026

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    Trenitalia FrecceTrenitalia2h 44m • 1 change
  •  → 

    Trenitalia FrecceTrenitalia3h 2m • 1 change
  •  → 

    Arrives next day

    Trenitalia FrecceTrenitalia10h 2m • 1 change

Departing Monday, November 16, 2026

  •  → 

    Trenitalia FrecceTrenitalia3h 2m • 1 change
  •  → 

    Arrives next day

    Trenitalia FrecceTrenitalia10h 2m • 1 change

Departing Tuesday, November 17, 2026

  •  → 

    Trenitalia FrecceTrenitalia2h 44m • 1 change
  •  → 

    Trenitalia FrecceTrenitalia3h 2m • 1 change

Frequently asked questions

Want to know about travelling from Pisa Centrale to Vatican Museums? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Pisa Centrale to Vatican Museums.ExpandLaunch map view
  • Distance: 345.4 km
  • Duration: 5h 2m

What companies run services between Pisa Centrale, Italy and Vatican Museums, Vatican City?

Trenitalia Frecce operates a train from Pisa Centrale to Roma Tiburtina 5 times a day. Tickets cost €45–80 and the journey takes 2h 9m.

Operators